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Landmark expents in molecular biology - Replication, Transcription, Translation & Genetic Code

What you'll learn
A deeper insight into major molecular mechanisms- replication, transcription, translation, and how they evolved
Meselsen-Stahl expent, Theta mode of replication, okazaki fragements and discontinous mode of replication
Discovery of mRNA, ribosome composition, direction of translation and protein synthesis
Discovery of RNA polymerase and mechanism of transcription
Path-breaking expental strats that shaped the world of molecular biology as we know now
DNA- protein interaction assays
How an approach, integrating knowledge from diverse fields such as chemistry, biochemistry and mathematics, led to the understanding of the composition of genetic material as well as the genetic code
Elucidation of the genetic code
Expental evidence for - DNA/RNA as the genetic material
Requirements
Students should have a basic knowledge in biology and chemistry.

An understanding of nucleic acids and their roles in information transfer would be an added advantage.
Description
This Online Molecular Genetics course focuses on understanding and appreciating the genius of great scientists who made significant contributions in molecular biology with limited resources during their s. Current advances in this field are due to their pioneering efforts. The objective of the course is to unravel those underlying thinking processes for furthering creative research and designing unique expental methods.In this online course in molecular biology, you'll learn about - Chal, biochal and structural evidence for DNA/RNA as genetic materialDNA -protein interactions expents that revealed the DNA sequence to which DNA interacting proteins bind toExpents unraveling the mechanism of DNA replication. Eg- Meselsen-stahl expentDiscovery of protein synthesis machinery- mRNA, tRNA and ribosomesExpents done to decipher the mechanism of transcriptionElucidation of the genetic codeAll these expents revealed the central dogma of molecular biology.Each section of this online course is packed with quizzes to apply the information you have learnt in the lectures.This course is for students with a basic background in biology and chemistry. This course comes with a 30-day money back guarantee, so there is nothing to lose.Enroll in the course today and learn how the molecular mechanisms at the Replication, transcription and translation level were deciphered.

Overview

Section 1: Introduction

Lecture 1 Introduction

Section 2: DNA/RNA as genetic material

Lecture 2 Chal evidence for genetic material

Lecture 3 Biochal evidence for Genetic material

Lecture 4 Structural evidence for Genetic material

Section 3: Assays for DNA-protein interactions

Lecture 5 Assays for DNA-protein interactions part 1

Lecture 6 Assays for DNA-protein interactions part 2

Section 4: Expents showing the mechanism of replication

Lecture 7 Meselsen and Stahl's expent

Lecture 8 Analogy for mode of replication

Lecture 9 mode of replication

Lecture 10 Semi-discontinuous replication

Lecture 11 concepts introduced

Lecture 12 RNA priming

Lecture 13 Techniques used for RNA priming

Section 5: Translation machinery

Lecture 14 Discovery of mRNA part 1

Lecture 15 Crick and Jacob hypothesis

Lecture 16 Discovery of mRNA part 2

Lecture 17 Ribosome composition

Lecture 18 discovery of tRNA

Lecture 19 Direction of translation and protein synthesis

Lecture 20 Amino acid specificity

Lecture 21 Discovery of N-formyl Met

Lecture 22 Coupled transcription and translation

Section 6: Transcription Features

Lecture 23 RNA polymerase subunits

Lecture 24 Techniques used

Lecture 25 Promoter Melting

Lecture 26 Terms

Lecture 27 Polymerase specificity

Lecture 28 RNA phosphodiester bond formation

Lecture 29 Terms used

Lecture 30 Elongation

Lecture 31 Transcription teation

Section 7: Elucidation of genetic code

Lecture 32 Theoretical basis for codon triplets

Lecture 33 Overlappion-overlapping nature of the genetic code

Lecture 34 Crick-Brenner hypothesis

Lecture 35 Expental evidence for genetic code part 1

Lecture 36 Expental evidence for genetic code part 2

Lecture 37 Expental evidence for Crick-Brenner Hypothesis

Lecture 38 Crick brenner validation

Section 8: Course Summary

Lecture 39 Wrap up

Lecture 40 BONUS

High school students, college freshers and research students who are fascinated to know how this field evolved through unconventional ways of thinking and would like to get deeper insights into expental strats that led to important discoveries.,This course is not for absolute bners who are looking for a typical molecular biology curriculum and also not for experts in the field who are looking for advanced knowledge .,This course would help research students in tapping into the collective historical wisdom of the pioneers, and use them as a guide in carving their own niche in further advancing this field.

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